I am very grateful to Queen Mary, University of London, for awarding me an academic position taking on a Principal Research Fellow-role within The School of Biological and Chemical Sciences. Prior to this, The Royal Society awarded me a University Research Fellowship (2001-2012), with further funding being awarded through the UK Government's Biotechnology and Biological Sciences Research Council (BBSRC; 2003 & 2007) and The Royal Society small grants scheme (2006). Other grants are listed below. The lab is engaged in projects with Japan, under the JST/CREST initiative "Structural characterisation of the transient macromolecular complexes engaged in photoacclimation" (2013-2019).
Recently, the
London Consortium for Electron Microscopy (LonCEM) has been awarded a major grant (March 2017), the lab being a named group within the QMUL partner's contribution.

The Royal Society University Research Fellowship (£273,040 + £386,464 + £194,000; extended to 30/09/2012).

I have held the following BBSRC grants (from their OASIS database):

Grant Reference: BBF0215261
Current Institution of Principal Investigator/Co-Applicant: Queen Mary, University of London
Institution of Grant: Queen Mary, University of London
Leader: PI, Nield J
Title: Molecular basis of FtsH function in the cyanobacterium Synechocystis PCC 6803
Edited Abstract: FtsH proteases, which are members of the AAA+ (for ATPase associated with various cellular activities) superfamily of proteins, play an important physiological role in the cyanobacterium, Synechocystis 6803, including the acclimation to various type of abiotic stress (e.g., light, heat and salt stress). A wide-ranging investigation into the structure and function of the four FtsH homologues found in Synechocystis 6803 will be conducted.
End date was: 29/05/12
Duration: 39 months
Total Value of Grant: £28,883

Grant Reference: B17532
Current Institution of Principal Investigator/Co-Applicant: Queen Mary, University of London, Imperial College London
Institution of Grant: Imperial College London
Leader: PI, Nield J; co-PI, Barber J
Title: Using C. reinhardtii as a model system for determining the macromolecular structure of PSI and PSII by high resolution electron microscopy
Conclusions: The transformable green alga, C. reinhardtii, was used as a model system to obtain structural information about the macromolecular organisation of photosystem I (PSI) and photosystem II (PSII), in higher plants and other photosynthetic eukaryotic organisms that contain chlorophyll a/b light harvesting complexes (LHC). Using electron cryo-microscopy and single particle analysis, a 3D structural model of the LHCII-PSII supercomplex of spinach was refined. Related studies were conducted to isolate and characterise a novel LHCI-PSI supercomplex, by negative stain electron microscopy (EM). Complementary analyses were also carried out using mutants of Chlamydomonas lacking PSI, PSII and LHCI and II subunits in order to aid the interpretation of the 3D maps obtained.
End date was: 1/01/06
Duration: 36 months
Total Value of Grant: £203,160

Grant Reference: C11886
Title: Elucidating the structure of photosystem two by cryoelectron microscopy and single particle analyses
Institution of grant: Imperial College London
Principal Investigator: Barber J currently at: Imperial College London
Co-Applicant: Nield J currently at: Queen Mary, University of London
Co-Applicant: Van Heel M currently at: Imperial College London
Conclusions: This work programme obtained a 3D structure of photosystem II (PSII) from spinach at 17 Angstroem resolution using cryo-electron microscopy and single particle analyses. In addition, a 3D structure of the LHCII-PSII supercomplex from Chlamydomonas reinhardtii was determined and compared to the similar supercomplex from spinach. All structures obtained were analysed in order to highlight similarities and differences with their 3D maps used as frameworks for incorporating structures of various subunits and subcomplexes obtained from X-ray and electron crystallography. The spatial relationship between the extrinsic proteins of the Oxygen Evolving Complex and the D1 and D2 proteins of the reaction centre was investigated.
Start date: 16/10/99; left project upon award of Royal Society Fellowship 01/10/01
Total Value of Grant: £204,841

Grant Reference: C06795
Title: Structure determination of a multi-subunit supercomplex of photosystem II by single particle analysis of cryo-electron micrographs
Institution of grant: Imperial College London
Principal Investigator: Barber J
Co-Applicant: Van Heel M
Post-doctoral researcher: Nield J
Conclusions: New and powerful techniques in the image processing of single particles from cryo-electron microscopy were used to reconstruct a 3D map of the multi-subunit supercomplex, photosystem II. This map was used to determine the position of subunits of this protein complex in order to understand the structural information obtained in the context of energy transfer, charge separation and water splitting.
Start date: 1/01/97 End date was: 30/09/99
Total Value of Grant: £173,054

I acknowledge all the
Journals that have published details of my co-authored research.

Website design & implementation by Jon Nield. Programs used: Rapidweaver 7 and, pre-2007, Dreamweaver 5.5.
Photo credits: My own work (see EXIF data), unless specifically noted in the webpage footer or on the image.